Experimental Studies on Porphyrin Metabolism in Various Heavy Metal Poisoning
نویسندگان
چکیده
منابع مشابه
Heavy Metal Poisoning in Birds
Heavy metal poisonings in birds most commonly occur from ingestion of substances containing lead or zinc. Lead that is ingested can be absorbed through the gastrointestinal tract and then taken up by soft tissues and eventually by bone. Lead affects all major organs and can cause damage to the gastrointestinal tract, red blood cells, kidneys and liver. Clinical signs of heavy metal toxicosis ma...
متن کاملISOTOPIC STUDIES OF PORPHYRIN AND HEMOGLOBIN METABOLISM II. THE BIOSYNTHESIS OF COPROPORPHYRIN III IN EXPERIMENTAL LEAD POISONING* BY MOISfiS GRINSTEIN,?
It is now well established that glycine is a direct nitrogenous precursor of hemoglobin protoporphyrin in rats (l), rabbits (Z), dogs (3), and humans (4), of coproporphyrin I in dogs and humans (3, 5), of uroporphyrin I in humans (5), and of stercobilin in humans (5, 6). It is well known that lead intoxication in rabbits is associated with prompt and marked increases of urinary coproporphyrin I...
متن کاملPorphyrin metabolism and barbiturate poisoning: observations on cases of acute and chronic poisoning.
The connexion between acute porphyria and barbiturate poisoning was pointed out by Waldenstrom (1939), who stated that practically all fatal cases of acute porphyria had been treated with large doses of barbiturates; on the other hand, the less severe cases as a rule received no such treatment, and further (Waldenstrom, 1940) in the majority of cases of acute porphyria large quantities of, for ...
متن کاملHeavy Metal Poisoning and Cardiovascular Disease
Cardiovascular disease (CVD) is an increasing world health problem. Traditional risk factors fail to account for all deaths from CVD. It is mainly the environmental, dietary and lifestyle behavioral factors that are the control keys in the progress of this disease. The potential association between chronic heavy metal exposure, like arsenic, lead, cadmium, mercury, and CVD has been less well de...
متن کاملHeavy metal poisoning: clinical presentations and pathophysiology.
Humans have had a long and tumultuous relationship with heavy metals. Their ubiquitous nature and our reliance on them for manufacturing have resulted at times in exposures sufficient to cause systemic toxicity. Their easy acquisition and potent toxicity have also made them popular choices for criminal poisonings. This article examines the clinical manifestation and pathophysiology of poisoning...
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ژورنال
عنوان ژورنال: Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)
سال: 1975
ISSN: 0021-5082,1882-6482
DOI: 10.1265/jjh.30.337